MEDD Australia | Chronic Pain Management | Activity

Tylah McDonald posted an update in the group Chronic Pain Management: Unpacking Pain: Opposite Neuronal Regulation in Acute […]

Thu, 03 Jul 2025 01:42:06 +1000

Unpacking Pain: Opposite Neuronal Regulation in Acute vs. Chronic Pain States. New research reveals a fundamental difference in how specific pain-related projection neurons in the brain’s medulla respond during acute versus chronic pain conditions. This discovery suggests a crucial regulatory mechanism in acute pain that, if absent,…

science.org

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Tylah McDonald posted an update in the group Chronic Pain Management: Epidural Steroids: Limited Efficacy for Radicular Pain […]

Wed, 02 Jul 2025 04:26:24 +1000

Epidural Steroids: Limited Efficacy for Radicular Pain & Spinal Stenosis. A major systematic review finds epidural steroid injections (ESIs) offer limited, primarily short-term benefits for pain and disability in radiculopathy and lumbar spinal stenosis, with insufficient evidence for long-term efficacy or for cervical…

neurology.org

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Tylah McDonald posted an update in the group Chronic Pain Management: High Co-occurrence of Depression and Anxiety in Adults […]

Wed, 02 Jul 2025 03:41:15 +1000

High Co-occurrence of Depression and Anxiety in Adults with Chronic Pain: A Global Review. A comprehensive systematic review and meta-analysis reveal that approximately 40% of adults living with chronic pain also experience clinically significant symptoms of depression and anxiety. This global analysis underscores the substantial mental…

jamanetwork.com

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Tylah McDonald posted an update in the group Chronic Pain Management: The FDA has approved a new drug, suzetrigine, to […]

Mon, 28 Apr 2025 04:13:47 +1000

The FDA has approved a new drug, suzetrigine, to treat moderate-to-severe pain and offers new approaches to pain management.

“Journavx” by Vertex Pharmaceuticals is the first non-opioid painkiller since that class first appeared on the market in the 1980s. Suzetrigine targets sodium channels specific to pain neurons, offering pain relief…

scientificamerican.com

What Is Journavx, the New Opioid-Free Painkiller from Vertex?

The nonaddictive painkiller suzetrigine (Journavx) is as effective for acute pain as a common opioid treatment

Tylah McDonald posted an update in the group Chronic Pain Management: How does pain-related fear in patients with chronic low […]

Sun, 13 Oct 2024 23:51:25 +1100

How does pain-related fear in patients with chronic low back pain affect their movement patterns during daily activities? This study investigates whether fear impacts spinal movement variability and what this means for clinical assessments.

https://www.nature.com/articles/s41598-024-73430-8

nature.com

Associations between pain-related fear and lumbar movement variability during activities of daily living in patients with chronic low back pain and healthy controls - Scientific Reports

Low back pain (LBP) is a global issue involving biological, psychological, and social factors. Pain-related fear has been shown to influence movement behavior, however, its association with some measures of movement behavior, such as spinal movement variability, remains inconclusive. To … Continue reading

Tylah McDonald posted an update in the group Chronic Pain Management: Researchers discovered a peptide that selectively […]

Mon, 25 Mar 2024 05:42:59 +1100

Researchers discovered a peptide that selectively inhibits pain signaling in sensory neurons and incorporated it into a viral-based gene therapy, offering a potential solution for treating chronic pain without addiction risk.

https://www.pnas.org/doi/10.1073/pnas.2217800120

pnas.org

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